I just finished watching the movie Deadgirl and I really liked it. It was an original take on on the zombie/vampire genre. In this age of sequels and remakes it was refreshing to see something new.
That being said it was a pretty sick and twisted movie. If you like horror with a bit of social commentary check it out.
If you are looking for another movie that will challenge your perceptions of the horror genre you should also check out KatieBird *Certifiable Crazy Person.
Finally, another movie I saw recently but which you should avoid is Feed. Interesting concept on the serial killer sub-genre but totally ridiculous.